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Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses

We provide a comprehensive genomic and epigenomic map of the more than 500,000 endogenous retroviruses (ERVs) and fragments that populate the intergenic regions of the human genome. The repressive epigenetic marks associated with the ERVs, particularly long terminal repeats (LTRs), show a remarkable...

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Publicat a:Genome Res
Autors principals: Ohtani, Hitoshi, Liu, Minmin, Zhou, Wanding, Liang, Gangning, Jones, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071641/
https://ncbi.nlm.nih.gov/pubmed/29970451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.234229.118
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