Role of DNA Methylation in Expression and Transmission of Porcine Endogenous Retroviruses

Porcine endogenous retroviruses (PERV) represent a major safety concern in pig-to-human xenotransplantation. To date, no PERV infection of a xenograft recipient has been recorded; however, PERVs are transmissible to human cells in vitro. Some recombinants of the A and C PERV subgroups are particular...

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Bibliografiske detaljer
Main Authors: Matoušková, Magda, Veselý, Pavel, Daniel, Petr, Mattiuzzo, Giada, Hector, Ralph D., Scobie, Linda, Takeuchi, Yasuhiro, Hejnar, Jiří
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807924/
https://ncbi.nlm.nih.gov/pubmed/23986605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03262-12
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