Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

The SK-BR-3 cell line is one of the most important models for HER2+ breast cancers, which affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged, although much of the variation is in complex and repetitive regions that may be underreported. Addressing this, we sequenced...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Nattestad, Maria, Goodwin, Sara, Ng, Karen, Baslan, Timour, Sedlazeck, Fritz J., Rescheneder, Philipp, Garvin, Tyler, Fang, Han, Gurtowski, James, Hutton, Elizabeth, Tseng, Elizabeth, Chin, Chen-Shan, Beck, Timothy, Sundaravadanam, Yogi, Kramer, Melissa, Antoniou, Eric, McPherson, John D., Hicks, James, McCombie, W. Richard, Schatz, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071638/
https://ncbi.nlm.nih.gov/pubmed/29954844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.231100.117
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker