A comprehensive characterization of cis-acting splicing-associated variants in human cancer

Although many driver mutations are thought to promote carcinogenesis via abnormal splicing, the landscape of splicing-associated variants (SAVs) remains unknown due to the complexity of splicing abnormalities. Here, we developed a statistical framework to systematically identify SAVs disrupting or n...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Shiraishi, Yuichi, Kataoka, Keisuke, Chiba, Kenichi, Okada, Ai, Kogure, Yasunori, Tanaka, Hiroko, Ogawa, Seishi, Miyano, Satoru
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071634/
https://ncbi.nlm.nih.gov/pubmed/30012835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.231951.117
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