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On the Relationship Between High-Order Linkage Disequilibrium and Epistasis
A plausible explanation for statistical epistasis revealed in genome wide association analyses is the presence of high order linkage disequilibrium (LD) between the genotyped markers tested for interactions and unobserved functional polymorphisms. Based on findings in experimental data, it has been...
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| Publicado no: | G3 (Bethesda) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071592/ https://ncbi.nlm.nih.gov/pubmed/29945968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200513 |
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