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Replication and Explorations of High-Order Epistasis Using a Large Advanced Intercross Line Pedigree

Dissection of the genetic architecture of complex traits persists as a major challenge in biology; despite considerable efforts, much remains unclear including the role and importance of genetic interactions. This study provides empirical evidence for a strong and persistent contribution of both sec...

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Detalhes bibliográficos
Main Authors: Pettersson, Mats, Besnier, Francois, Siegel, Paul B., Carlborg, Örjan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140984/
https://ncbi.nlm.nih.gov/pubmed/21814519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002180
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