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An Improved Method for Quantitative Trait Loci Detection and Identification of Within-Line Segregation in F(2) Intercross Designs

We present a new flexible, simple, and powerful genome-scan method (flexible intercross analysis, FIA) for detecting quantitative trait loci (QTL) in experimental line crosses. The method is based on a pure random-effects model that simultaneously models between- and within-line QTL variation for si...

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Detalhes bibliográficos
Main Authors: Rönnegård, Lars, Besnier, Francois, Carlborg, Örjan
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323818/
https://ncbi.nlm.nih.gov/pubmed/18430952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.083162
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