Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease Etiology

Idiopathic scoliosis (IS) is a structural lateral spinal curvature of ≥10° that affects up to 3% of otherwise healthy children and can lead to life-long problems in severe cases. It is well-established that IS is a genetic disorder. Previous studies have identified genes that may contribute to the I...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Baschal, Erin E., Terhune, Elizabeth A., Wethey, Cambria I., Baschal, Robin M., Robinson, Kandice D., Cuevas, Melissa T., Pradhan, Shreyash, Sutphin, Brittan S., Taylor, Matthew R. G., Gowan, Katherine, Pearson, Chad G., Niswander, Lee A., Jones, Kenneth L., Miller, Nancy H.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2018
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071588/
https://ncbi.nlm.nih.gov/pubmed/29930198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200290
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