Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli

Ruminococcin A (RumA) is a lanthipeptide with high activity against pathogenic clostridia and is naturally produced by the strict anaerobic bacterium Ruminococcus gnavus E1, isolated from human intestine. Cultivating R. gnavus E1 is challenging, limiting high-quality production, further biotechnolog...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Microbiol
Päätekijät: Ongey, Elvis L., Giessmann, Robert T., Fons, Michel, Rappsilber, Juri, Adrian, Lorenz, Neubauer, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Microbiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071512/
https://ncbi.nlm.nih.gov/pubmed/30093894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01688
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