Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli

Ruminococcin A (RumA) is a lanthipeptide with high activity against pathogenic clostridia and is naturally produced by the strict anaerobic bacterium Ruminococcus gnavus E1, isolated from human intestine. Cultivating R. gnavus E1 is challenging, limiting high-quality production, further biotechnolog...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Ongey, Elvis L., Giessmann, Robert T., Fons, Michel, Rappsilber, Juri, Adrian, Lorenz, Neubauer, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071512/
https://ncbi.nlm.nih.gov/pubmed/30093894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01688
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