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Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity

Botulinum neurotoxins (BoNTs) are highly successful protein therapeutics. Over 40 naturally occurring BoNTs have been described thus far and, of those, only 2 are commercially available for clinical use. Different members of the BoNT family present different biological properties but share a similar...

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Podrobná bibliografie
Vydáno v:Toxins (Basel)
Hlavní autoři: Fonfria, Elena, Elliott, Mark, Beard, Matthew, Chaddock, John A., Krupp, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071219/
https://ncbi.nlm.nih.gov/pubmed/29973505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10070278
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