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Effect of Botulinum Toxin A on Urothelial-Release of ATP and Expression of SNARE Targets Within the Urothelium

AIMS: Botulinum neurotoxin serotype A (BoNT/A) has emerged as an effective treatment of urinary bladder overactivity. Intravesical lipotoxin (BoNT/A delivery using liposomes), which may target the urothelium, is effective in blocking acetic acid induced hyperactivity in animals. The objective of thi...

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Detalhes bibliográficos
Main Authors: Hanna-Mitchell, Ann T., Wolf-Johnston, Amanda S., Barrick, Stacey R., Kanai, Anthony J., Chancellor, Michael B., de Groat, William C., Birder, Lori A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035459/
https://ncbi.nlm.nih.gov/pubmed/24167028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nau.22508
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