HDV Can Constrain HBV Genetic Evolution in HBsAg: Implications for the Identification of Innovative Pharmacological Targets

Chronic HBV + HDV infection is associated with greater risk of liver fibrosis, earlier hepatic decompensation, and liver cirrhosis hepatocellular carcinoma compared to HBV mono-infection. However, to-date no direct anti-HDV drugs are available in clinical practice. Here, we identified conserved and...

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Publié dans:Viruses
Auteurs principaux: Colagrossi, Luna, Salpini, Romina, Scutari, Rossana, Carioti, Luca, Battisti, Arianna, Piermatteo, Lorenzo, Bertoli, Ada, Fabeni, Lavinia, Minichini, Carmine, Trimoulet, Pascale, Fleury, Hervé, Nebuloso, Elena, De Cristofaro, Maria, Cappiello, Giuseppina, Spanò, Alberto, Malagnino, Vincenzo, Mari, Terenzio, Barlattani, Angelo, Iapadre, Nerio, Lichtner, Miriam, Mastroianni, Claudio, Lenci, Ilaria, Pasquazzi, Caterina, De Sanctis, Giuseppe Maria, Galeota Lanza, Alfonso, Stanzione, Maria, Stornaiuolo, Gianfranca, Marignani, Massimo, Sarmati, Loredana, Andreoni, Massimo, Angelico, Mario, Ceccherini-Silberstein, Francesca, Perno, Carlo-Federico, Coppola, Nicola, Svicher, Valentina
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071122/
https://ncbi.nlm.nih.gov/pubmed/29987240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10070363
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