Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein

The C terminus of HSC70-interacting protein (CHIP, STUB1) is a ubiquitously expressed cytosolic E3-ubiquitin ligase. CHIP-deficient mice exhibit cardiovascular stress and motor dysfunction before premature death. This phenotype is more consistent with animal models in which master regulators of auto...

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Publicat a:J Neurosci
Autors principals: Lizama, Britney N., Palubinsky, Amy M., Raveendran, Vineeth A., Moore, Annah M., Federspiel, Joel D., Codreanu, Simona G., Liebler, Daniel C., McLaughlin, BethAnn
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070662/
https://ncbi.nlm.nih.gov/pubmed/29934347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0699-18.2018
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