Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress

Apoptosis signal-regulating kinase 1 (ASK1) is a key sensor kinase in the mitogen-activated protein kinase pathway that transduces cellular responses to oxidants and electrophiles. ASK1 is regulated by a large, dynamic multiprotein signalosome complex, potentially including over 90 reported ASK1-int...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Federspiel, Joel D., Codreanu, Simona G., Palubinsky, Amy M., Winland, Ama J., Betanzos, Carlos Morales, McLaughlin, BethAnn, Liebler, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083084/
https://ncbi.nlm.nih.gov/pubmed/27006476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.057364
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