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BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines
Beta-site amyloid-precursor-protein cleaving enzyme 1 (BACE1) is the rate limiting protease in the production of the amyloid-beta peptide (Aβ), which is considered to be the causative agent in the pathogenesis of Alzheimer’s Disease (AD). Therefore, the therapeutic potential of pharmacological BACE1...
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| Vydáno v: | Front Aging Neurosci |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6070607/ https://ncbi.nlm.nih.gov/pubmed/30093858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00229 |
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