Evolution of high pathogenicity of H5 avian influenza virus: haemagglutinin cleavage site selection of reverse-genetics mutants during passage in chickens

Low pathogenicity avian influenza viruses (LPAIVs) are generally asymptomatic in their natural avian hosts. LPAIVs can evolve into highly pathogenic forms, which can affect avian and human populations with devastating consequences. The switch to highly pathogenic avian influenza virus (HPAIV) from L...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Luczo, Jasmina M., Tachedjian, Mary, Harper, Jennifer A., Payne, Jean S., Butler, Jeffrey M., Sapats, Sandra I., Lowther, Suzanne L., Michalski, Wojtek P., Stambas, John, Bingham, John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070550/
https://ncbi.nlm.nih.gov/pubmed/30068964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29944-z
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