Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein analyses

FUS-DDIT3 belongs to the FET (FUS, EWSR1, and TAF15) family of fusion oncogenes, which collectively are considered to be key players in tumor development. Even though over 90% of all myxoid liposarcomas (MLS) have a FUS-DDIT3 gene fusion, there is limited understanding of the signaling pathways that...

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Dettagli Bibliografici
Pubblicato in:Lab Invest
Autori principali: Svec, David, Dolatabadi, Soheila, Thomsen, Christer, Cordes, Nicole, Shannon, Mark, Fitzpatrick, Paul, Landberg, Göran, Åman, Pierre, Ståhlberg, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group US 2018
Soggetti:
Technical Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070472/
https://ncbi.nlm.nih.gov/pubmed/29588491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0046-3
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