The Myxoid/Round Cell Liposarcoma Fusion Oncogene FUS-DDIT3 and the Normal DDIT3 Induce a Liposarcoma Phenotype in Transfected Human Fibrosarcoma Cells

Myxoid/round cell liposarcoma (MLS/RCLS) is the most common subtype of liposarcoma. Most MLS/RCLS carry a t(12;16) translocation, resulting in a FUS-DDIT3 fusion gene. We investigated the role of the FUS-DDIT3 fusion in the development of MLS/RCLS in FUS-DDIT3- and DDIT3-transfected human HT1080 sar...

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Detalhes bibliográficos
Main Authors: Engström, Katarina, Willén, Helena, Kåbjörn-Gustafsson, Christina, Andersson, Carola, Olsson, Marita, Göransson, Melker, Järnum, Sofia, Olofsson, Anita, Warnhammar, Elisabeth, Åman, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
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Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606602/
https://ncbi.nlm.nih.gov/pubmed/16651630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050872
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