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FUS::DDIT3 Fusion Protein in the Development of Myxoid Liposarcoma and Possible Implications for Therapy

The FUS::DDIT3 fusion protein, formed by the chromosomal translocation t (12;16) (q13;p11), is found in over 90% of myxoid liposarcoma (MLS) cases and is a crucial protein in its development. Many studies have explored the role of FUS::DDIT3 in MLS, and the prevailing view is that FUS::DDIT3 inhibit...

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Principais autores: Xutong Hou, Wenjin Shi, Wenxin Luo, Yuwen Luo, Xuelin Huang, Jing Li, Ning Ji, Qianming Chen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-10-01
Serier:Biomolecules
Fag:
chromosomal translocation
FUS::DDIT3 fusion protein
myxoid liposarcoma
Online adgang:https://www.mdpi.com/2218-273X/14/10/1297
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