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Bioinformatic expansion and discovery of thiopeptide antibiotics

Thiopeptides are members of the ribosomally synthesized and posttranslationally modified peptides (RiPP) family of natural products. Most characterized thiopeptides display nanomolar potency towards Gram-positive bacteria by blocking protein translation with several being produced at the industrial...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Schwalen, Christopher J., Hudson, Graham A., Kille, Bryce, Mitchell, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070396/
https://ncbi.nlm.nih.gov/pubmed/29983054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03896
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