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Exploration and stabilization of Ras1 mating zone: A mechanism with positive and negative feedbacks

In mating fission yeast cells, sensing and response to extracellular pheromone concentrations occurs through an exploratory Cdc42 patch that stochastically samples the cell cortex before stabilizing towards a mating partner. Active Ras1 (Ras1-GTP), an upstream regulator of Cdc42, and Gap1, the GTPas...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Khalili, Bita, Merlini, Laura, Vincenzetti, Vincent, Martin, Sophie G., Vavylonis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070293/
https://ncbi.nlm.nih.gov/pubmed/30028833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006317
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