Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation

To cope with intrinsic and environmental stress, cancer cells rely on adaptive pathways more than non-transformed counterparts. Such non-oncogene addiction offers new therapeutic targets and strategies to overcome chemoresistance. In an attempt to study the role of adaptive pathways in acquired drug...

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Veröffentlicht in:PLoS One
Hauptverfasser: Battista, R. Alessia, Resnati, Massimo, Facchi, Cecilia, Ruggieri, Elena, Cremasco, Floriana, Paradiso, Francesca, Orfanelli, Ugo, Giordano, Leone, Bussi, Mario, Cenci, Simone, Milan, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070274/
https://ncbi.nlm.nih.gov/pubmed/30067838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201621
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