Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells

BACKGROUND: Lipotoxicity plays an important role in the pathogenesis of kidney injury. Our previous study demonstrated that activation of local renin-angiotensin system (RAS) was involved in saturated free fatty acids palmitic acid (PA)-induced tubular cell injuries. The current study aims to invest...

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Опубликовано в: :Lipids Health Dis
Главные авторы: Qiu, Miaojuan, Li, Suchun, Jin, Lizi, Feng, Pinning, Kong, Yonglun, Zhao, Xiaoduo, Lin, Yu, Xu, Yunyun, Li, Chunling, Wang, Weidong
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069859/
https://ncbi.nlm.nih.gov/pubmed/30064425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0818-1
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