Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection

Porcine reproductive and respiratory syndrome virus (PRRSV) has a narrow host cell tropism, limited to cells of the monocyte/macrophage lineage. CD163 protein is expressed at high levels on the surface of specific macrophage types, and a soluble form is circulating in blood. CD163 has been described...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Burkard, Christine, Opriessnig, Tanja, Mileham, Alan J., Stadejek, Tomasz, Ait-Ali, Tahar, Lillico, Simon G., Whitelaw, C. Bruce A., Archibald, Alan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069206/
https://ncbi.nlm.nih.gov/pubmed/29925651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00415-18
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