Caricamento...
Growing a gasdermin pore in membranes of pyroptotic cells
Inflammasome‐activated caspase‐1, caspase‐11, caspase‐4, and caspase‐5 cleave GSDMD to unleash its N‐terminal gasdermin‐N domain (GSDMD(N) (term)) that perforates the plasma membrane to execute pyroptosis and stimulate inflammation. The mechanism underlying GSDMD(N) (term) pore formation is unclear....
Salvato in:
| Pubblicato in: | EMBO J |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6068444/ https://ncbi.nlm.nih.gov/pubmed/29997177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100067 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|