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Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence

Childhood pilocytic astrocytomas (PA) are low‐grade tumours with an excellent prognosis. However, a minority, particularly those in surgically inaccessible locations, have poorer long‐term outcome. At present, it is unclear whether anatomical location in isolation, or in combination with underlying...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Sexton‐Oates, Alexandra, Dodgshun, Andrew, Hovestadt, Volker, Jones, David T. W., Ashley, David M., Sullivan, Michael, MacGregor, Duncan, Saffery, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068350/
https://ncbi.nlm.nih.gov/pubmed/28388012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12062
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