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Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery

Molecular similarity is a key concept in drug discovery. It is based on the assumption that structurally similar molecules frequently have similar properties. Assessment of similarity between small molecules has been highly effective in the discovery and development of various drugs. Especially, two...

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Bibliografski detalji
Izdano u:Front Chem
Glavni autori: Kumar, Ashutosh, Zhang, Kam Y. J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068280/
https://ncbi.nlm.nih.gov/pubmed/30090808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00315
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