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Advances in the Development of Shape Similarity Methods and Their Application in Drug Discovery

Molecular similarity is a key concept in drug discovery. It is based on the assumption that structurally similar molecules frequently have similar properties. Assessment of similarity between small molecules has been highly effective in the discovery and development of various drugs. Especially, two...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Kumar, Ashutosh, Zhang, Kam Y. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068280/
https://ncbi.nlm.nih.gov/pubmed/30090808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00315
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