Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons

Our understanding of the molecular processes underlying Alzheimer’s disease (AD) is still limited, hindering the development of effective treatments, and highlighting the need for human-specific models. Advances in identifying components of the amyloid cascade are progressing, including the role of...

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書目詳細資料
發表在:Front Neurosci
Main Authors: Robbins, Jacqueline P., Perfect, Leo, Ribe, Elena M., Maresca, Marcello, Dangla-Valls, Adrià, Foster, Evangeline M., Killick, Richard, Nowosiad, Paulina, Reid, Matthew J., Polit, Lucia Dutan, Nevado, Alejo J., Ebner, Daniel, Bohlooly-Y, Mohammad, Buckley, Noel, Pangalos, Menelas N., Price, Jack, Lovestone, Simon
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068261/
https://ncbi.nlm.nih.gov/pubmed/30090055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00504
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