Neoadjuvant PF-05280014 (a potential trastuzumab biosimilar) versus trastuzumab for operable HER2+ breast cancer

BACKGROUND: This randomised, double-blind study compared pharmacokinetics, efficacy, safety and immunogenicity of PF-05280014 (potential trastuzumab biosimilar) and trastuzumab reference product (Herceptin) sourced from the European Union (trastuzumab-EU) as neoadjuvant treatment for operable human...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Lammers, Philip E., Dank, Magdolna, Masetti, Riccardo, Abbas, Richat, Hilton, Fiona, Coppola, Jennifer, Jacobs, Ira
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068194/
https://ncbi.nlm.nih.gov/pubmed/30002437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0147-1
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