Comparative Nonclinical Assessments of the Proposed Biosimilar PF-05280014 and Trastuzumab (Herceptin(®))

BACKGROUND AND OBJECTIVES: Trastuzumab (Herceptin(®)) is a humanized monoclonal antibody (mAb) that binds to the HER2 protein. PF-05280014 is being developed as a potential biosimilar to trastuzumab products marketed in the United States (trastuzumab-US) and European Union (trastuzumab-EU). Nonclini...

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Hlavní autoři: Hurst, Susan, Ryan, Anne M., Ng, Chee-Keng, McNally, James M., Lorello, Leslie G., Finch, Gregory L., Leach, Michael W., Ploch, Stephen A., Fohey, Josh A., Smolarek, Teresa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2014
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Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176567/
https://ncbi.nlm.nih.gov/pubmed/25001079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-014-0103-4
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