Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

Cellular oxidative stress plays a vital role in the pathological process of neural damage in cerebral ischemia/reperfusion (I/R). The breast cancer susceptibility protein 1 (BRCA1), a tumor suppressor, can modulate cellular antioxidant response and DNA repair. Yet the role of BRCA1 in cerebral I/R i...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Xu, Pengfei, Liu, Qian, Xie, Yi, Shi, Xiaolei, Li, Yunzi, Peng, Mengna, Guo, Hongquan, Sun, Rui, Li, Juanji, Hong, Ye, Liu, Xinfeng, Xu, Gelin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068089/
https://ncbi.nlm.nih.gov/pubmed/30014904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.06.012
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