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Effects of Disease-Causing Mutations on the Conformation of Human Apolipoprotein A-I in Model Lipoproteins
Plasma high-density lipoproteins (HDL) are protein-lipid nanoparticles that transport lipids and protect against atherosclerosis. Human apolipoprotein A-I (apoA-I) is the principal HDL protein whose mutations can cause either aberrant lipid metabolism or amyloid disease. Hydrogen-deuterium exchange...
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| Published in: | Biochemistry |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6067968/ https://ncbi.nlm.nih.gov/pubmed/30004693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00538 |
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