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Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

The hair cell mechanotransduction (MET) channel complex is essential for hearing, yet it’s molecular identity and structure remain elusive. The transmembrane channel–like 1 (TMC1) protein localizes to the site of the MET channel, interacts with the tip-link responsible for mechanical gating, and gen...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ballesteros, Angela, Fenollar-Ferrer, Cristina, Swartz, Kenton Jon
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067890/
https://ncbi.nlm.nih.gov/pubmed/30063209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38433
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