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Potent Antimycobacterial Activity of the Pyridoxal Isonicotinoyl Hydrazone Analog 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone: A Lipophilic Transport Vehicle for Isonicotinic Acid Hydrazide

The rise in drug-resistant strains of Mycobacterium tuberculosis is a major threat to human health and highlights the need for new therapeutic strategies. In this study, we have assessed whether high-affinity iron chelators of the pyridoxal isonicotinoyl hydrazone (PIH) class can restrict the growth...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Pharmacol
मुख्य लेखकों: Ellis, Samantha, Kalinowski, Danuta S., Leotta, Lisa, Huang, Michael L. H., Jelfs, Peter, Sintchenko, Vitali, Richardson, Des R., Triccas, James A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067633/
https://ncbi.nlm.nih.gov/pubmed/24243647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.090357
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