Long term adaptation of a microbial population to a permanent metabolic constraint: overcoming thymineless death by experimental evolution of Escherichia coli

BACKGROUND: To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for experimentally evolving natural isolates of wild-type species or recombinant strains. This goal is beyond the scope of current continuous cult...

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Detalhes bibliográficos

Publicado no:	BMC Biotechnol
Principais autores:	de Crécy-Lagard, Valérie A, Bellalou, Jacques, Mutzel, Rupert, Marlière, Philippe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2001
Assuntos:	Methodology Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11737878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6750-1-10
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