Neuroprotective Efficacy and Pharmacokinetic Behavior of Novel Anti-Inflammatory Para-Phenyl Substituted Diindolylmethanes in a Mouse Model of Parkinson’s Disease

There are currently no registered drugs that slow the progression of neurodegenerative diseases, in part because translation from animal models to the clinic has been hampered by poor distribution to the brain. The present studies examined a selected series of para-phenyl–substituted diindolylmethan...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: De Miranda, Briana R., Miller, James A., Hansen, Ryan J., Lunghofer, Paul J., Safe, Stephen, Gustafson, Daniel L., Colagiovanni, Dorothy, Tjalkens, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067390/
https://ncbi.nlm.nih.gov/pubmed/23318470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201558
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