Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells

Mucin-type O-glycans decorate >80% of secretory and cell surface proteins and contribute to health and disease. However, dynamic alterations in the O-glycome are poorly understood because current O-glycomic methodologies are not sufficiently sensitive nor quantitative. Here we describe a novel is...

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Pubblicato in:Glycobiology
Autori principali: Kudelka, Matthew R, Nairn, Alison V, Sardar, Mohammed Y, Sun, Xiaodong, Chaikof, Elliot L, Ju, Tongzhong, Moremen, Kelley W, Cummings, Richard D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067123/
https://ncbi.nlm.nih.gov/pubmed/29390058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy005
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