Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells

Hepatocyte-like cells (HLCs) derived from human pluripotent stem cells (hPSCs) offer a promising cell resource for disease modeling and transplantation. However, differentiated HLCs exhibit an immature phenotype and comprise a heterogeneous population. Thus, a better understanding of HLC differentia...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Li, Shuang, Li, Mushan, Liu, Xiaojian, Yang, Yuanyuan, Wei, Yuda, Chen, Yanhao, Qiu, Yan, Zhou, Tingting, Feng, Zhuanghui, Ma, Danjun, Fang, Jing, Ying, Hao, Wang, Hui, Musunuru, Kiran, Shao, Zhen, Zhao, Yongxu, Ding, Qiurong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066908/
https://ncbi.nlm.nih.gov/pubmed/29861165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.05.001
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