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Microglia Responses to Pro-inflammatory Stimuli (LPS, IFNγ+TNFα) and Reprogramming by Resolving Cytokines (IL-4, IL-10)

Microglia respond to CNS injuries and diseases with complex reactions, often called “activation.” A pro-inflammatory phenotype (also called classical or M1 activation) lies at one extreme of the reactivity spectrum. There were several motivations for this study. First, bacterial endotoxin (lipopolys...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Lively, Starlee, Schlichter, Lyanne C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066613/
https://ncbi.nlm.nih.gov/pubmed/30087595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00215
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