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Normal CA1 place fields but discoordinated network discharge in a Fmr1-null mouse model of fragile X syndrome
Silence of FMR1 causes loss of fragile X mental retardation protein (FMRP) and dysregulated translation at synapses, resulting in the intellectual disability and autistic symptoms of Fragile X Syndrome (FXS). Synaptic dysfunction hypotheses for how intellectual disabilities like cognitive inflexibil...
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| Pubblicato in: | Neuron |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066593/ https://ncbi.nlm.nih.gov/pubmed/29358017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.12.043 |
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