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Structural visualization of RNA polymerase III transcription machineries
RNA polymerase III (Pol III) transcription initiation requires the action of the transcription factor IIIB (TFIIIB) and is highly regulated. Here, we determine the structures of Pol III pre-initiation complexes (PICs) using single particle cryo-electron microscopy (cryo-EM). We observe stable Pol II...
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| Publicat a: | Cell Discov |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066478/ https://ncbi.nlm.nih.gov/pubmed/30083386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0044-z |
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