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Structural visualization of RNA polymerase III transcription machineries

RNA polymerase III (Pol III) transcription initiation requires the action of the transcription factor IIIB (TFIIIB) and is highly regulated. Here, we determine the structures of Pol III pre-initiation complexes (PICs) using single particle cryo-electron microscopy (cryo-EM). We observe stable Pol II...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Discov
Egile Nagusiak: Han, Yan, Yan, Chunli, Fishbain, Susan, Ivanov, Ivaylo, He, Yuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066478/
https://ncbi.nlm.nih.gov/pubmed/30083386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0044-z
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