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Genetic Cartography of Longevity in Humans and Mice: Current Landscape and Horizons

Aging is a complex and highly variable process. Heritability of longevity among humans and other species is low, and this has given rise to the idea that it may be futile to search for gene variants that control rates of aging. We argue that the problem is mainly due to low power and the genetic and...

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Библиографические подробности
Опубликовано в: :Biochim Biophys Acta
Главные авторы: Hook, Michael, Roy, Suheeta, Williams, Evan G., Sleiman, Maroun Bou, Mozhui, Khyobeni, Nelson, James F., Lu, Lu, Auwerx, Johan, Williams, Robert W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066442/
https://ncbi.nlm.nih.gov/pubmed/29410319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.01.026
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