Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is among the most prevalent of the adult-onset muscular dystrophies. FSHD causes a loss of muscle mass and function, resulting in severe debilitation and reduction in quality of life. Currently, only the symptoms of FSHD can be treated, and such treatmen...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cruz, Joseph M., Hupper, Nicole, Wilson, Liz S., Concannon, John B., Wang, Yuan, Oberhauser, Berndt, Patora-Komisarska, Krystyna, Zhang, Yunyu, Glass, David J., Trendelenburg, Anne-Ulrike, Clarke, Brian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066320/
https://ncbi.nlm.nih.gov/pubmed/29899111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002633
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