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The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture

The discovery that MptpA (low-molecular-weight protein tyrosine phosphatase A) from Mycobacterium tuberculosis (Mtb) has an essential role for Mtb virulence has motivated research of tyrosine-specific phosphorylation in Mtb and other pathogenic bacteria. The phosphatase activity of MptpA is regulate...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Niesteruk, Anna, Jonker, Hendrik R. A., Richter, Christian, Linhard, Verena, Sreeramulu, Sridhar, Schwalbe, Harald
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066317/
https://ncbi.nlm.nih.gov/pubmed/29884774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000120
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