DNA methylation regulates the neonatal CD4(+) T-cell response to pneumonia in mice

Pediatric acute lung injury, usually because of pneumonia, has a mortality rate of more than 20% and an incidence that rivals that of all childhood cancers combined. CD4(+) T-cells coordinate the immune response to pneumonia but fail to function robustly among the very young, who have poor outcomes...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: McGrath-Morrow, Sharon A., Ndeh, Roland, Helmin, Kathryn A., Chen, Shang-Yang, Anekalla, Kishore R., Abdala-Valencia, Hiam, D'Alessio, Franco R., Collaco, J. Michael, Singer, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066312/
https://ncbi.nlm.nih.gov/pubmed/29866884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003589
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