PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C

HIV-1 subtype C (HIV-1C) may duplicate longer amino acid stretches in the p6 Gag protein, leading to the creation of an additional Pro–Thr/Ser–Ala–Pro (PTAP) motif necessary for viral packaging. However, the biological significance of a duplication of the PTAP motif for HIV-1 replication and pathoge...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Sharma, Shilpee, Arunachalam, Prabhu S., Menon, Malini, Ragupathy, Viswanath, Satya, Ravi Vijaya, Jebaraj, Joshua, Aralaguppe, Shambhu Ganeshappa, Rao, Chaitra, Pal, Sreshtha, Saravanan, Shanmugam, Murugavel, Kailapuri G., Balakrishnan, Pachamuthu, Solomon, Suniti, Hewlett, Indira, Ranga, Udaykumar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Microbiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066301/
https://ncbi.nlm.nih.gov/pubmed/29773649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815829
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