Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive (ALK+) and NPM-ALK-negative (ALK−) anaplastic large-cell lymphoma (ALCL...

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Pubblicato in:Cell Rep
Autori principali: Hassler, Melanie R., Pulverer, Walter, Lakshminarasimhan, Ranjani, Redl, Elisa, Hacker, Julia, Garland, Gavin D., Merkel, Olaf, Schiefer, Ana-Iris, Simonitsch-Klupp, Ingrid, Kenner, Lukas, Weisenberger, Daniel J., Weinhaeusel, Andreas, Turner, Suzanne D., Egger, Gerda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066089/
https://ncbi.nlm.nih.gov/pubmed/27705804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.018
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